Where the Atmosphere and Food Make for a Dining Adventure at our Sanibel Island Seafood Restaurant

Among Sanibel seafood restaurants, George and Wendy’s Sanibel Seafood Grille offers truly outstanding service, atmosphere, and cuisine. We offer lunch, dinner, late night menu, and daily changing specials. The focus of all our menus is fresh, local, and fun. We also have a full bar with an extensive wine list, 20 beers on tap, a lot of local, domestic and craft beer bottles, and some fun and fresh, handcrafted signature drinks on our list including mojitos, martinis, and lots of other tropical craft cocktail favorites.

George and Wendy’s Sanibel Seafood Grille is honored to have been voted “Best Place for Entertainment of the Islands 2017.” We offer a variety of live entertainment almost every night of the week featuring musicians locally and from afar. Our Sanibel Island restaurant is also an art gallery displaying a few of our local artists’ work that is sure to make your dining experience one of a kind.

George and Wendy’s Sanibel Seafood Grille offers several dining areas to enjoy: our main dining room, garden setting patio, sports bar/lounge, and our back room dining. Each room offers its own unique experience. Home to the Chicago Bears and Buffalo Bills fans offering a round of free jello shots to bar patrons for each Bears and Bills touchdown adds to the fun. We welcome all football fans to come in and cheer for your favorite team. The lush, pet-friendly tropical garden patio is located outside the main entrance of our seafood restaurant on Sanibel Island. Enjoy lunch, dinner, and cocktails surrounded by the natural beauty of Sanibel Island. The back dining room offers a more offbeat dining experience that is also available for family gatherings, corporate parties, meetings, rehearsal dinners or special event gatherings. George and Wendy’s Sanibel Seafood Grille is the perfect place for your next Sanibel adventure, and we look forward to making your experience with us memorable. Call us to plan your next special occasion or make a reservation for your next dining experience. We accommodate for both large and small parties.

Sanibel Seafood Grille Trip Advisor - Traveler's Choice
Sanibel Seafood Grille Best of The Islands
Image of Sanibel Seafood Grille Best of the Island Badge - Best Bar and Best Beer Selection on Sanibel
Best Bar, Best Place to Watch the Game, Best Place for Entertainment, and Best Bartender on Sanibel

weekly specials

BBQ Ribs - Sanibel Island Restaurant



BBQ Ribs

Full rack of slow-cooked baby back ribs
w/ fries & slaw $18

Prime Rib - Sanibel Island Restaurant



Prime Rib

10 oz  slow-cooked Prime Rib w/mash & veg $20




Blackened Salmon

with Pineapple Salsa $20

Coconut Shrimp - Sanibel Island Restaurant



Coconut Shrimp

Hand-rolled Coconut Shrimp w/rice & veg $18

Fried Haddock - Sanibel island Seafood Restaurant



Fried Haddock

Beer-battered Haddock w/fries & slaw $15

Along with our weekly Monday-Friday specials, our menu hosts an extensive list of tasty options. Our appetizers offer a perfect number of choices to get the night started. From our crispy Ahi Tuna Nachos, Fried Pickle Spears, Roasted Garlic & Brie, and so much more, the choices are almost endless! For the main course, we have even more options to choose from. At George & Wendy’s Sanibel Seafood Grille, our flatbreads are sure to please with a classic Cheese or a Buffalo Shrimp. We also offer options From The Turf, and The Surf including the Rib Eye Steak or the Piña Colada Snapper. Along with these, we offer tacos or pasta options as well as classic salads and soups. There’s always fresh seafood at our fish house. To finish off the night, choose from a selection of our delicious locally homemade desserts!

For customers with special requests, we offer an extensive gluten-free lunch and dinner menu as well. We offer gluten-free flatbreads, tacos with corn tortillas, pastas served over gluten-free brown rice noodles, and wraps crafted with gluten-free tortillas. We also offer a number of gluten-free soups! Ask your waiter if our soup of the day is gluten-free!

lunch menu
dinner menu
late night menu


sanibel’s famous handcrafted drinks

Sanibel Seafood Grille Signature Drinks

Bloody Mary

Epic Bloody Mary

Garnished with a Bacon-wrapped Hard Boiled Egg, Cocktail Shrimp, Bleu Cheese Stuffed Olives & a Pickle sprinkled and rimmed w/ Old Bay Seasoning.



Only the best!  From Classic, Skinny or our “Wow” Ultimate Margarita….to adventurous Coco-Nutty, Heatwave, Ain’t No Saint, or Light My Fire Margaritas. Yumm!”

Mojitos - Sanibel Seafood Grille Signature Drinks


Mojitos Our Way!

Are you the Classic, Berry Naked or the Prickly Pear type?  Have fun with these!

Martinis - Sanibel Seafood Grille Signature Drinks



It’s Martini Time!  Handcrafted and made especially to delight the senses.  Enjoy our Flirty and Dirty, Cucumber Chill, French, Lemon Drop or Strawberry Fields to name a few.

Frozen Drinks - Sanibel Seafood Grille Signature Drinks

On The Rocks

Fun On The Rocks

Was it the Old Fashion Redemption, Islander, Tropical Heat, Toasted Coconut or the Hurricane that brought you back for more?

With the largest selection of signature cocktails, beer and wine menu, our Sanibel Seafood Grille has a drink to suit anyone’s taste. From specialty Bloody Marys, to Margaritas & Martinis with a twist, Mojitos, Frozen Drinks, and a number of Fun On The Rocks, there is so much to choose from! If fruity drinks are not your style, no worries! We have over 20 beers on tap including Lagers, Ales, and IPAs, as well as a number of seasonal choices as well. We also offer Wendy’s Wine List, which contains an extensive number of Red & White options.

Check out the drinks menu to see our full list.

drinks menu

live music

live entertainment

Not only do we offer a large menu and many specialty drinks, at George and Wendy’s Sanibel Seafood Grille we keep the party going with live entertainment almost every night of the week.  Local musicians play most Sundays, Mondays, Wednesdays, and Thursdays.  Full Bands play Friday and Saturday nights.  So, bring your dancing shoes and “swing” by to enjoy a bite to eat along with a show

Relentless Fire

December 4 @ 9:00 pm - 11:55 pm

Aaron Seyferth, Variety 7-11pm

December 5 @ 7:00 pm - 11:00 pm

Jenny Ve, Variety 7-11pm

December 7 @ 7:00 pm - 11:00 pm

Buckeye Ken & Friends

December 8 @ 7:00 pm - 11:00 pm

entertainment calendar

local art display

Sanibel Island is a special place for George and Wendy, and they want the guests of their Sanibel seafood restaurant to be able to relax, enjoy a good meal, have a great experience, and take in all that Sanibel Island has to offer. To add to your dining experience, our Sanibel restaurant is also an art gallery, hosting local art pieces from artists around the island!


Great food, and great service. Torrey has been our waiter each visit and he has a great personality and his suggestions are always good. The special I had was salmon stuffed with their great crab cakes was the best meal I have had on the island. The crab cakes are really good as an appetizer. Torrey has made each trip to the grille a great experience.

Lewis W.

On a mini vacation from the Fort Lauderdale-Hollywood area. GREAT service! Kasey was great. Very attentive staff! My husband had the blackened grouper with potato salad and loved it! I had the roast beef with garlic potatoes which was amazing. Not to mention the game day drink specials. Definitely will be back!

Lindsey A.

My husband and I shared two sandwiches for lunch – blackened haddock and patty melt burger. We got fries as sides. Both were out of this world. Prepared perfectly and we didn’t wait long. The service was fantastic and the decor beautiful. Very clean and well maintained. Will definitely return.


Food was fantastic and the friendly service was excellent. This restaurant is a must do while on the island. We visited three times within the week of our stay. Julia (the manager) did a wonderful job of making sure customers were pleased with their entrees. Keep up the great food and service and this corner grill will be around for many years to come!